one of the hand-drawn signs i used at AWA09. the original is about 9" tall.
zangetsu, along with her sister myoujou, were at the top of my display, announcing my name.
drawn on vellum bristol, inked with copic multiliners, colored with prismacolor markers and colored pencils.
background added with photoshop CS3.
generally, dark colors streak far more noticeably than lighter ones, so when i color darker areas, i try to do a "double" layer of ink...hard to explain D: but as i'm coloring i just spend twice as long laying color down in those spots, if that makes any sense. of course, this does make the color darker, so it might be best to start out slightly lighter and do 2-3 layers of color to get the shade you want. (and be aware of any extra bleeding this will cause on the paper; color just short of the lines and/or put a sheet of scrap paper under your work if necessary, some papers bleed more than others)
don't wait for the ink to dry and then go back over it, that'll just make everything blotchy...stick to coloring small areas at a time. this includes shading, if you're going for a blended look and not cel shaded. fully color and shade one body part at a time, or one chunk of hair, etc.
if you WANT cel shading though, make sure each area of ink is dry before adding shadows :]